Poly-A tail: Difference between revisions

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The Poly-A tail is a polyadenylate sequence which is added to the 3' terminus of a eukaryotic [[mRNA|mRNA]] during RNA processing. A Poly-A tail can consist up to 200 nucleotides of [[adenosine monophosphate|adenosine monophosphate]], which greatly increases the stability of the mRNA. Before the addition of the Poly-A tail, the 3' terminus of a eukaryotic mRNA has been modified by&nbsp;exonuclease digestion.This allows the mRNA sequence to act as a substrate for the extension of Poly-A tail<ref>Hartl D., Ruvolo M. (2012) Genetics: Analysis of Genes and Genomes, 8th edition, Burlington, MA : Jones&amp;amp;amp;Bartlett Learning (Page 358)</ref>.
The Poly-A tail is a polyadenylate sequence which is added to the 3' terminus of a eukaryotic [[MRNA|mRNA]] during RNA processing. A Poly-A tail can consist up to 200 nucleotides of [[Adenosine monophosphate|adenosine monophosphate]], which greatly increases the stability of the mRNA. Before the addition of the Poly-A tail, the 3' terminus of a eukaryotic mRNA has been modified by&nbsp;[[Exonuclease|exonuclease]] digestion.This allows the mRNA sequence to act as a substrate for the extension of Poly-A tail<ref>Hartl D., Ruvolo M. (2012) Genetics: Analysis of Genes and Genomes, 8th edition, Burlington, MA : Jones&amp;amp;amp;amp;Bartlett Learning (Page 358)</ref>.  


=== References ===
=== References ===


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Latest revision as of 08:22, 16 October 2015

The Poly-A tail is a polyadenylate sequence which is added to the 3' terminus of a eukaryotic mRNA during RNA processing. A Poly-A tail can consist up to 200 nucleotides of adenosine monophosphate, which greatly increases the stability of the mRNA. Before the addition of the Poly-A tail, the 3' terminus of a eukaryotic mRNA has been modified by exonuclease digestion.This allows the mRNA sequence to act as a substrate for the extension of Poly-A tail[1].

References

  1. Hartl D., Ruvolo M. (2012) Genetics: Analysis of Genes and Genomes, 8th edition, Burlington, MA : Jones&amp;amp;amp;Bartlett Learning (Page 358)