Primary structure: Difference between revisions
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The primary structure is the first structure of a [[Protein|protein]] made. It is the underlying basis of how the protein folds up and what conformational shape it takes. It is made of a string of [[ | The primary structure is the first structure of a [[Protein|protein]] made. It is the underlying basis of how the [[Proteins|protein]] folds up and what conformational shape it takes. It is made of a linear string of [[Amino acid|amino acids]] ([[Polypeptide|polypeptide]] chain) which have been coded for by [[Codon|codons]] by [[DNA|DNA]] base sequences in the translation process. Peptide bonds form between amino acids to attach them together<ref>Burrows C, Elder E, Hayden C, McCurrie R, Rogers R, Thompson H, Towle J, Tyler M (eds) 2012, AS-Level Biology, the complete course for OCR, Coordination Group Publications, Newcastle Upon Tyne p.108</ref>. Each [[Amino acid|amino acid]] is individually different and the different chemistries of the side chains allow the [[Polypeptide|polypeptide chain]] to fold up in a unique way allowing a specific function for that [[Protein|protein]] <ref>Molecular Biology of the Cell, 5th edition, Bruce Alberts et al, p127, p131.</ref>. | ||
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Latest revision as of 14:07, 2 December 2015
The primary structure is the first structure of a protein made. It is the underlying basis of how the protein folds up and what conformational shape it takes. It is made of a linear string of amino acids (polypeptide chain) which have been coded for by codons by DNA base sequences in the translation process. Peptide bonds form between amino acids to attach them together[1]. Each amino acid is individually different and the different chemistries of the side chains allow the polypeptide chain to fold up in a unique way allowing a specific function for that protein [2].