Sodium-glucose symporter: Difference between revisions

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[[Sodium acetate|Sodium]]-[[Glucose 6-phosphate|glucose]] [[Symporter]] is a transmembrane protein and is an example of sodium-driven [[Secondary active transport]] that occurs in the epithelial cells of the [[Small intestines|small intestines]]. The sodium-glucose symporter is found on the [[Apical membrane]] of the [[Epithelal cells|epithelal cells]]. The sodium and glucose bind to the symporter and are simultaneously both co-transported into the epithelial cells. The sodium driven-glucose symporter uses the potential free energy stored in the [[Sodium electrochemical gradient|sodium electrochemical gradient]] (low sodium concentration inside the epithelial cells) established by [[Sodium-potassium pump]]. Therefore, the sodium influx from the lumen to the epithelial cell is coupled with glucose transport.
[[Sodium acetate|Sodium]]-[[Glucose 6-phosphate|glucose]]&nbsp;[[Symporter]]&nbsp;is a transmembrane protein and is an example of sodium-driven&nbsp;[[Secondary active transport]]&nbsp;that occurs in the epithelial cells of the [[Small intestines|small intestines<ref>Alberts et al. Molecular Biology of The Cell (6th Edition), Garland Sciences; New York: 2015 (page 605)</ref>]].&nbsp;The sodium-glucose symporter is found on the&nbsp;[[Apical membrane]]&nbsp;of the [[Epithelal cells|epithelal cells<ref>Alberts et al. Molecular Biology of The Cell (6th Edition), Garland science; New York: 2015 (page 605)</ref>]]. The sodium and glucose bind to the symporter and are simultaneously both co-transported into the epithelial cells. The sodium driven-glucose symporter uses the potential free energy stored in the [[Sodium electrochemical gradient|sodium electrochemical gradient]] (low sodium concentration inside the epithelial cells) established by&nbsp;[[Sodium-potassium pump|Sodium-potassium pump<ref>Alberts et al. Molecular Biology of The Cell (6th Edition), Garland Science; New York: 2015 (page 606-608)</ref>]]. Therefore, the sodium influx from the lumen to the epithelial cell is coupled with glucose transport.  
 
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Revision as of 20:28, 2 December 2015

Sodium-glucose Symporter is a transmembrane protein and is an example of sodium-driven Secondary active transport that occurs in the epithelial cells of the small intestines[1]. The sodium-glucose symporter is found on the Apical membrane of the epithelal cells[2]. The sodium and glucose bind to the symporter and are simultaneously both co-transported into the epithelial cells. The sodium driven-glucose symporter uses the potential free energy stored in the sodium electrochemical gradient (low sodium concentration inside the epithelial cells) established by Sodium-potassium pump[3]. Therefore, the sodium influx from the lumen to the epithelial cell is coupled with glucose transport.




References

  1. Alberts et al. Molecular Biology of The Cell (6th Edition), Garland Sciences; New York: 2015 (page 605)
  2. Alberts et al. Molecular Biology of The Cell (6th Edition), Garland science; New York: 2015 (page 605)
  3. Alberts et al. Molecular Biology of The Cell (6th Edition), Garland Science; New York: 2015 (page 606-608)