1,4 glycosidic bond: Difference between revisions

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[[Image:Alpha and Beta Glycosidic Bonds.png|right|Alpha and Beta Glycosidic Bonds.png]] Glycosidic bonds are formed due to a [[Condensation reaction|condensation reaction]] between two [[Monosaccharides|monosaccharides]] to form a [[Polysaccharide|polysaccharide]]. A condensation reaction is when two molecules combine to create a simple molecule and [[Water|water]] is eliminated. The glycosidic bond can be [[Hydrolysis|hydrolysed]] by the addition of a water molecule.  
[[Image:Alpha and Beta Glycosidic Bonds.png|right|Alpha and Beta Glycosidic Bonds.png]] Glycosidic bonds are formed due to a [[Condensation reaction|condensation reaction]] between two [[Monosaccharides|monosaccharides]] to form a [[Polysaccharide|polysaccharide]] (polymers, or many units of sugars). A condensation reaction is when two molecules combine to create a simple molecule and [[Water|water]] is eliminated. The glycosidic bond can be [[Hydrolysis|hydrolysed]] by the addition of a water molecule to reform two monosaccharides (monomers, or single units of sugars).  


The [[1,4 glcosidic bond|1,4 glycosidic bond is]] formed between the [[Carbon|carbon]]-1 of one monosaccharide and carbon-4 of the other. There are are two types - 1,4 alpha and 1,4 beta glycosidic bonds. 1,4 alpha glycosidic bonds are formed when the OH on the carbon-1 is below the glucose ring; while 1,4 beta glycosidic bonds are formed when the OH is above the plane<ref>Jeremy M. Berg, John L. Tymoczko, Lubert Stryer . Biochemistry Seventh Edition Freeman</ref><ref>http://dictionary.reference.com/browse/Condensation_reaction - 29/11/2013</ref>. When two alpha D-glucose, a more occurring isomer of [https://en.wikipedia.org/wiki/Glucose glucose ]compared to the L-glucose, form a glycosidic linkage, the term is known as a α-1,4-glycosidic bond<ref>Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/</ref><ref>Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/</ref>.<br>
The [[1,4 glcosidic bond|1,4 glycosidic bond is]] formed between the [[Carbon|carbon]]-1 of one monosaccharide and carbon-4 of the other. There are are two types&nbsp;of&nbsp;glycosidic&nbsp;bonds&nbsp;- 1,4 alpha and 1,4 beta glycosidic bonds. 1,4 alpha glycosidic bonds are formed when the OH on the carbon-1 is below the glucose ring; while 1,4 beta glycosidic bonds are formed when the OH is above the plane<ref>Jeremy M. Berg, John L. Tymoczko, Lubert Stryer . Biochemistry Seventh Edition Freeman</ref><ref>http://dictionary.reference.com/browse/Condensation_reaction - 29/11/2013</ref>. When two alpha D-glucose molecules join together a more commonly occurring isomer of [https://en.wikipedia.org/wiki/Glucose glucose ]compared to the L-glucose, form a glycosidic linkage, the term is known as a α-1,4-glycosidic bond<ref>Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/</ref><ref>Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/</ref>.<br>


=== References  ===
=== References  ===


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Revision as of 14:49, 17 October 2016

Alpha and Beta Glycosidic Bonds.png
Alpha and Beta Glycosidic Bonds.png

Glycosidic bonds are formed due to a condensation reaction between two monosaccharides to form a polysaccharide (polymers, or many units of sugars). A condensation reaction is when two molecules combine to create a simple molecule and water is eliminated. The glycosidic bond can be hydrolysed by the addition of a water molecule to reform two monosaccharides (monomers, or single units of sugars).

The 1,4 glycosidic bond is formed between the carbon-1 of one monosaccharide and carbon-4 of the other. There are are two types of glycosidic bonds - 1,4 alpha and 1,4 beta glycosidic bonds. 1,4 alpha glycosidic bonds are formed when the OH on the carbon-1 is below the glucose ring; while 1,4 beta glycosidic bonds are formed when the OH is above the plane[1][2]. When two alpha D-glucose molecules join together a more commonly occurring isomer of glucose compared to the L-glucose, form a glycosidic linkage, the term is known as a α-1,4-glycosidic bond[3][4].

References

  1. ↑ Jeremy M. Berg, John L. Tymoczko, Lubert Stryer . Biochemistry Seventh Edition Freeman
  2. ↑ http://dictionary.reference.com/browse/Condensation_reaction - 29/11/2013
  3. ↑ Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/
  4. ↑ Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/
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