Α-Ketoglutarate dehydrogenase: Difference between revisions
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Pronounced alpha-ketoglutarate dehydrogenase this is a complex formed from three kinds of enzymes found in the citric acid cycle (CAC).<br>It catalyses the oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA | Pronounced alpha-ketoglutarate dehydrogenase, this is a complex formed from three kinds of [[Enzymes|enzymes]] found in the [[Citric acid cycle|citric acid cycle ]](CAC).<br>It catalyses the [[Oxidative decarboxylation|oxidative decarboxylation]] of alpha-ketoglutarate to [[Succinyl CoA|succinyl CoA]]<ref>Berg J, Tymoczko J, Gatto G, Stryer L. Biochemistry. 8th ed. New York: W.H. Freeman; 2015. p. 505</ref><sup></sup>. | ||
The reaction is as follows:<br>alpha-Ketoglutarate + NAD + CoA -----► Succinyl CoA + | The reaction is as follows:<br>alpha-Ketoglutarate + NAD + CoA -----► Succinyl CoA + CO<sub>2</sub> + NADH <sup></sup> | ||
=== References === | |||
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Latest revision as of 11:08, 5 December 2016
Pronounced alpha-ketoglutarate dehydrogenase, this is a complex formed from three kinds of enzymes found in the citric acid cycle (CAC).
It catalyses the oxidative decarboxylation of alpha-ketoglutarate to succinyl CoA[1].
The reaction is as follows:
alpha-Ketoglutarate + NAD + CoA -----► Succinyl CoA + CO2 + NADH
References
- ↑ Berg J, Tymoczko J, Gatto G, Stryer L. Biochemistry. 8th ed. New York: W.H. Freeman; 2015. p. 505