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A transmembrane | A transmembrane protein is a [[Protein|protein]] which is associated with the [[Lipid bilayer|lipid bilayer]] in the [[Cell membranes|membrane]]. The protein runs right through the membrane with both [[Cytosol|cytosolic]] and extracellular domains. Proteins can have several transmembrane domains if its polypeptide chain repeatedly crosses the lipid bilayer in the membrane<ref>http://www.ncbi.nlm.nih.gov/books/NBK21570/(accessed 19/10/14)</ref>. Transmembrane proteins are [[Amphipathic|amphipathic]]; the [[Hydrophobic|hydrophobic]] regions interact with lipid tails inside the lipid bilayer and the [[Hydrophillic|hydrophillic]] regions are exposed <ref>Alberts,B., Johnson,A., Lewis,J., Raff,M., Roberts,K. and Walter,P. (2008) Molecular Biology of the Cell, 5th Edition, 630</ref>. | ||
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Latest revision as of 08:32, 19 October 2017
A transmembrane protein is a protein which is associated with the lipid bilayer in the membrane. The protein runs right through the membrane with both cytosolic and extracellular domains. Proteins can have several transmembrane domains if its polypeptide chain repeatedly crosses the lipid bilayer in the membrane[1]. Transmembrane proteins are amphipathic; the hydrophobic regions interact with lipid tails inside the lipid bilayer and the hydrophillic regions are exposed [2].
References
- ↑ http://www.ncbi.nlm.nih.gov/books/NBK21570/(accessed 19/10/14)
- ↑ Alberts,B., Johnson,A., Lewis,J., Raff,M., Roberts,K. and Walter,P. (2008) Molecular Biology of the Cell, 5th Edition, 630