Immunoglobulin: Difference between revisions
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Immunoglobulins are [[Antibody|antibody]] molecules. They are proteins used in the immune response to identify and | Immunoglobulins are [[Antibody|antibody]] [[Molecules|molecules]]. They are [[Proteins|proteins]] used in the [[Immune response|immune response]] to identify and attach to [[Antigens|antigens]]. There are five classes of immunoglobulin - [[IgA|IgA]], [[IgD|IgD]], [[IgE|IgE]], [[IgG|IgG]] and [[IgM|IgM]]. All of the classes have two identical heavy chains which are bound to two identical light chains. The classes are distinguished by their structure and function, where for example, [[IgM|IgM]] is a pentamer and [[IgA|IgA is]] a dimer<ref>Lodish, HF (2013). Molecular cell biology. 7th ed. New York: W.H. Freeman . 1068-1069.</ref>. Each class plays a different role in adapive immune response. | ||
Immunogolbulin molecules have different heavy chains depending on the class (IgM, A, D, G, E): | |||
*IgM - μ chains | |||
*IgA - α chains | |||
*IgD - δ chains | |||
*IgG - γ chains | |||
*IgE - ε chains<ref>Berg, JM. Tymoczko, JL. Stryer, L. (2012) Biochemistry (7), p.1022-1023.</ref> | |||
=== Reference === | |||
<references /> | |||
Latest revision as of 06:56, 20 October 2017
Immunoglobulins are antibody molecules. They are proteins used in the immune response to identify and attach to antigens. There are five classes of immunoglobulin - IgA, IgD, IgE, IgG and IgM. All of the classes have two identical heavy chains which are bound to two identical light chains. The classes are distinguished by their structure and function, where for example, IgM is a pentamer and IgA is a dimer[1]. Each class plays a different role in adapive immune response.
Immunogolbulin molecules have different heavy chains depending on the class (IgM, A, D, G, E):
- IgM - μ chains
- IgA - α chains
- IgD - δ chains
- IgG - γ chains
- IgE - ε chains[2]