E. coli: Difference between revisions

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A [[Gram-negative|gram negative]], rod shaped bacterium that is mostly&nbsp;[[Coli|harmless]], but some strains&nbsp;can cause serious illness&nbsp;<ref>http://www.cdc.gov/ecoli/general/index.html</ref>. Commonly used in genetic engineering to mass produce proteins by inserting recombinant [[Plasmid|plasmids]]&nbsp;(e.g. to produce insulin). It is also used as a model organism because it can be easily manipulated, has a short generation time and its genome has been sequenced.<br>  
A [[Gram-negative|gram negative]], rod-shaped bacterium that is mostly harmless, but some strains can cause serious illness<ref>http://www.cdc.gov/ecoli/general/index.html</ref>. ''E. coli ''bacteria was discovered in 1885 by the German bacteriologist Theodor Escherich<ref>Feng, Peter, et al., “Enumeration of Escherichia coli and the Coliform Bacteria,” in BACTERIOLOGICAL ANALYTICAL MANUAL (8th Ed. 2002)</ref>. Commonly used in genetic engineering to mass produce [[Proteins|proteins]] by inserting recombinant [[Plasmid|plasmids]] (e.g. to produce [[Insulin receptor|insulin]]). It is also used as a model organism because it can be easily manipulated, has a short generation time and its [[Genome|genome]] has been sequenced. Urinary tract infections and especially ''E. coli'' intestinal infection can be caused by making contact with faeces of humans and animals<ref>Cold F, Health E, Disease H, Management P, Conditions S, Problems S et al. E. Coli Infection From Food or Water-Topic Overview [Internet]. WebMD. 2016 [cited 5 December 2016]. Available from: http://www.webmd.com/a-to-z-guides/tc/e-coli-infection-topic-overview#1</ref>.


See&nbsp;[[Escherichia coli|Escherichia coli]] for more details.  
See [[Escherichia coli|Escherichia coli]] for more details.  


=== References ===
=== References ===


<references />
<references />

Latest revision as of 08:55, 25 November 2017

A gram negative, rod-shaped bacterium that is mostly harmless, but some strains can cause serious illness[1]. E. coli bacteria was discovered in 1885 by the German bacteriologist Theodor Escherich[2]. Commonly used in genetic engineering to mass produce proteins by inserting recombinant plasmids (e.g. to produce insulin). It is also used as a model organism because it can be easily manipulated, has a short generation time and its genome has been sequenced. Urinary tract infections and especially E. coli intestinal infection can be caused by making contact with faeces of humans and animals[3].

See Escherichia coli for more details.

References

  1. http://www.cdc.gov/ecoli/general/index.html
  2. Feng, Peter, et al., “Enumeration of Escherichia coli and the Coliform Bacteria,” in BACTERIOLOGICAL ANALYTICAL MANUAL (8th Ed. 2002)
  3. Cold F, Health E, Disease H, Management P, Conditions S, Problems S et al. E. Coli Infection From Food or Water-Topic Overview [Internet]. WebMD. 2016 [cited 5 December 2016]. Available from: http://www.webmd.com/a-to-z-guides/tc/e-coli-infection-topic-overview#1