Hippocampal synaptic plasticity

 Hippocampal synaptic plasticity is the relationship between the neuronal memory & cellular mechanisms and synaptic plasticity of the hippocampus . There are studies present which indicate that suggest hippocampal functions are important for higher cognitive function (e.g. impairment leads to cognitive problems in Huntingtons) . However, approaches are being brought in to help repair and improve damage to hippocampal synaptic plasticity - for example, Leptin-deficient mice have shown to have imparired hippocampal synaptic plascity. Increasing Leptin levels made long-term potentiation possible and improved the memory of the deficient mice .