Hippocampal synaptic plasticity: Difference between revisions
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Hippocampal synaptic plasticity is the relationship between the [[neuronal memory|neuronal memory]] and cellular mechanisms and [[synaptic plasticity|synaptic plasticity]] of the [[hippocampus|hippocampus]]<ref>https://www.ncbi.nlm.nih.gov/pubmed/16678906</ref>. There are studies present which indicate that suggest hippocampal functions are important for higher cognitive function (e.g. impairment leads to cognitive problems in [[Huntington's_Disease|Huntington's]])<ref>https://www.nature.com/articles/s41467-018-06675-3</ref>. However, approaches are being brought in to help repair and improve damage to hippocampal synaptic plasticity - for example, [[Leptin|Leptin]]-deficient mice have shown to have impaired hippocampal synaptic plasticity. Increasing Leptin levels made long-term potentiation possible and improved the memory of the deficient mice<ref>https://www.ncbi.nlm.nih.gov/pubmed/16678906</ref>. | |||
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Latest revision as of 12:11, 18 October 2018
Hippocampal synaptic plasticity is the relationship between the neuronal memory and cellular mechanisms and synaptic plasticity of the hippocampus[1]. There are studies present which indicate that suggest hippocampal functions are important for higher cognitive function (e.g. impairment leads to cognitive problems in Huntington's)[2]. However, approaches are being brought in to help repair and improve damage to hippocampal synaptic plasticity - for example, Leptin-deficient mice have shown to have impaired hippocampal synaptic plasticity. Increasing Leptin levels made long-term potentiation possible and improved the memory of the deficient mice[3].