Basal lamina: Difference between revisions
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Basal lamina, a thin but tough and flexible membrane that is not made from cells purely. Basal lamina composed of laminin, type IV, XVIII collagen, nidogen, perlecan and fibronectin<ref>Cell Biology,2017:505-524</ref>. They are normally found in bone, [[Tendon|tendon]] and the dermal layer of the [[Skin|skin]]. It not only surrounds [[Epithelial cells|epithelial cells]] it also surrounds nonepithelial cells. Its primary function is to separate cells from the surrounding [[Connective tissue|connective tissue]]. Besides having a simple structural function it also has filtering roles in the [[Kidney|kidney]] glomerulus. They are able to determine cell polarity, regulating [[Cell|cell]] [[Metabolism|metabolism]], [[Protein|protein]] organization in adjacent [[Plasma membrane|plasma membranes]], cell survival and etc.<ref>Molecular Biology Of The Cell (Fifth Edition) Page 1164-1165 )</ref><ref>Molecular Biology Of The Cell (Fifth Edition)</ref>. | |||
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Latest revision as of 06:39, 23 October 2018
Basal lamina, a thin but tough and flexible membrane that is not made from cells purely. Basal lamina composed of laminin, type IV, XVIII collagen, nidogen, perlecan and fibronectin[1]. They are normally found in bone, tendon and the dermal layer of the skin. It not only surrounds epithelial cells it also surrounds nonepithelial cells. Its primary function is to separate cells from the surrounding connective tissue. Besides having a simple structural function it also has filtering roles in the kidney glomerulus. They are able to determine cell polarity, regulating cell metabolism, protein organization in adjacent plasma membranes, cell survival and etc.[2][3].