T cell receptors: Difference between revisions
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A T-Cell receptor is a molecule that can be found on the surface of [[T Lymphocytes|T Lymphocytes]] (T-Cells). T-Cells are part of the [[ | A T-Cell receptor is a protein [[Molecule|molecule]] that can be found on the surface of [[T Lymphocytes|T Lymphocytes]] (T-Cells). T-Cells are part of the [[Immune system|immune system]] and are responsible for many of the [[Immune response|immune responses]] that lead to [[Allergic reaction|allergic reactions]], transplanted organ rejections and [[Autoimmune disease|autoimmune diseases]]<ref>http://www.tcells.org/scientific/abTCR/</ref>. T-Cells circulate around the body and scan for abnormalities using their T receptors. When T cell receptor binds to antigen presented by the MHC class I/II molecules, signals are sent into the T cell<ref>https://www.sciencedirect.com/science/article/pii/S0960982205004884</ref>. The T-Cell receptors are heterodimers as they consist of two different protein chains. The chains are non-covalently associated with a complex of several polypeptides called [[CD3 antigens|CD3 antigens]]. | ||
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Latest revision as of 10:01, 3 December 2018
A T-Cell receptor is a protein molecule that can be found on the surface of T Lymphocytes (T-Cells). T-Cells are part of the immune system and are responsible for many of the immune responses that lead to allergic reactions, transplanted organ rejections and autoimmune diseases[1]. T-Cells circulate around the body and scan for abnormalities using their T receptors. When T cell receptor binds to antigen presented by the MHC class I/II molecules, signals are sent into the T cell[2]. The T-Cell receptors are heterodimers as they consist of two different protein chains. The chains are non-covalently associated with a complex of several polypeptides called CD3 antigens.