ATPase: Difference between revisions
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Revision as of 12:06, 10 January 2011
An ATPase is a group on enzymes in which ATP is hydrolyzed to ADP + Pi. ATPase is used in a large veriaty of cellular activities from the binding of DnaA to gene to amino acid degradation[1]. ATPase's are often used to pump ions across the cell membrane against their concentration gradient, know ions are that show this are H+, Na+, Cu2+, some also transport phospholipids with amino acid head groups[2].
The most commonly know ATPase is the sodium/potassium pump which actively transports three sodium ions out of the cell and two potassium ions into the cell for each ATP that it hydrolyzes setting up an electrochemical gradient[3]. Without this particular ATPase as with many others the body simply could not function correctly, thus ATPase's are extremely important enzymes within the cell.
References
- ↑ ( Biochemistry, 6th Edition, Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, W. H. Freeman and Company, New York, 2008)
- ↑ ( Biochemistry, 6th Edition, Jeremy M. Berg, John L. Tymoczko, Lubert Stryer, W. H. Freeman and Company, New York, 2008)
- ↑ (http://www.weizmann.ac.il/Biological_Chemistry/scientist/Karlish/steve_karlish.pdf , Professor Steven J D Karlish, Weizman institute of science, 2008)