Initiation of DNA Replication: Difference between revisions

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[[DNA]] replication is initiated from fixed origins which includes repeated sequences. For initiation of replication, two things are essential:
[[DNA]] replication is initiated from fixed origins which includes repeated sequences. For initiation of replication, two things are essential:  


*A [[nucleotide]] sequence that binds to initiation proteins.
*A [[Nucleotide]] sequence that binds to initiation proteins.


*Generation of a primer which can be extended with the help of [[DNA&nbsp;polymerase]]&nbsp;by adding nucleotides.&nbsp;<ref>Mathews et al., (2000) Biochemistry 3rd Edition, Pg 909</ref>
*Generation of a primer which can be extended with the help of [[DNA polymerase]]&nbsp;by adding nucleotides.&nbsp;<ref>Mathews, Van Holde, Ahern, 2000. Biochemistry. 3rd ed. Benjamin Cummings. Pg 909.</ref>

Revision as of 13:43, 25 November 2011

DNA replication is initiated from fixed origins which includes repeated sequences. For initiation of replication, two things are essential:

  • A Nucleotide sequence that binds to initiation proteins.
  • Generation of a primer which can be extended with the help of DNA polymerase by adding nucleotides. [1]
  1. Mathews, Van Holde, Ahern, 2000. Biochemistry. 3rd ed. Benjamin Cummings. Pg 909.