Initiation of DNA Replication: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
100636417 (talk | contribs)
No edit summary
100636417 (talk | contribs)
No edit summary
Line 1: Line 1:
[[DNA]] replication is initiated from fixed origins which includes repeated sequences. For initiation of replication, two things are essential:  
[[DNA]] replication is initiated from fixed origins which includes repeated sequences. <ref>Mathews et al. 2000. Biochemistry. 3rd Edition. Benjamin Cummings. Pg 909.</ref>&nbsp;For initiation of replication, two things are essential:  


*A [[Nucleotide]] sequence that binds to initiation proteins.
*A [[Nucleotide]] sequence that binds to initiation proteins.


*Generation of a primer which can be extended with the help of [[DNA polymerase]]&nbsp;by adding nucleotides.&nbsp;<ref>Mathews, Van Holde, Ahern, 2000. Biochemistry. 3rd ed. Benjamin Cummings. Pg 909.</ref>
*Generation of a primer which can be extended with the help of [[DNA polymerase]]&nbsp;by adding nucleotides.&nbsp;

Revision as of 13:46, 25 November 2011

DNA replication is initiated from fixed origins which includes repeated sequences. [1] For initiation of replication, two things are essential:

  • A Nucleotide sequence that binds to initiation proteins.
  • Generation of a primer which can be extended with the help of DNA polymerase by adding nucleotides. 
  1. Mathews et al. 2000. Biochemistry. 3rd Edition. Benjamin Cummings. Pg 909.