Cofactor: Difference between revisions
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Many [[Enzyme|enzymes]] require the presence of cofactors to become catalytically active. An enzyme without its cofactor is an [[Apoenzyme|apoenzyme]], whereas the complete catalytically active complex is called a [[Holoenzyme|holoenzyme]]. | Many [[Enzyme|enzymes]] require the presence of cofactors to become catalytically active. An enzyme without its cofactor is an [[Apoenzyme|apoenzyme]], whereas the complete catalytically active complex is called a [[Holoenzyme|holoenzyme]]. | ||
Cofactors are small molecules and are generally required to perform functions that cannot be performed by the standard amino acids. They can be subdivided into two groups: | Cofactors are small [[molecules|molecules]] and are generally required to perform functions that cannot be performed by the standard [[amino acids|amino acids]]. They can be subdivided into two groups: | ||
*Metals | *Metals | ||
*Small organic molecules (coenzymes)<ref>Berg, J.M., Tymoczko, J.L. and Stryer, L., 2011. Biochemistry 7th ed. New York: W.H. Freeman amd Company.</ref> | *Small organic molecules ([[coenzyme|coenzymes]])<ref>Berg, J.M., Tymoczko, J.L. and Stryer, L., 2011. Biochemistry 7th ed. New York: W.H. Freeman amd Company.</ref> | ||
=== References === | |||
<references /> | <references /> | ||
Latest revision as of 15:27, 2 December 2011
Many enzymes require the presence of cofactors to become catalytically active. An enzyme without its cofactor is an apoenzyme, whereas the complete catalytically active complex is called a holoenzyme.
Cofactors are small molecules and are generally required to perform functions that cannot be performed by the standard amino acids. They can be subdivided into two groups:
References
- ↑ Berg, J.M., Tymoczko, J.L. and Stryer, L., 2011. Biochemistry 7th ed. New York: W.H. Freeman amd Company.