Enzyme-substrate complex: Difference between revisions

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Enzyme-Substrate (ES) complexes are formed during [[enzyme|enzyme]] catalysed chemical reactions.  
Enzyme-Substrate (ES) complexes are formed during [[Enzyme|enzyme]] catalysed chemical reactions.  
 
Every enzyme is equipt with a 'cleft' in its structure which is complementary to a particular [[substrate|substrate]]. This is known as the active site. As well as shape, specificity of the active site is developed further via the [[amino acid|amino acid]] R-Groups&nbsp;within&nbsp;the&nbsp;site. These groups will interact specifically with the substrate molecule(s).[[https://docs.google.com/viewer?a=v&q=cache:Tn0x9PalpIkJ:www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf+enzyme+substrate+complex&hl=en&gl=uk&pid=bl&srcid=ADGEESinQz_Nw7C9lQYmplfliEswGAdvSyRx0aqr91j0UUF_y51PABTPgupe6supWcqudck5HgOKFbgnmCU-1rzngFubqzwP8zOZWQoUlM5Yxc3x0R_eMQMYqT7BxkkSqnb5M22ygi3f&sig=AHIEtbSTALob3Xfcnm8CLj2rhZKL97OWwA docs.google.com/viewer]]&nbsp;The ES&nbsp;complex is the state in which the active site of the enzyme is [[non-covalently bound|non-covalently bound]] to the substrate [[molecule|molecule]](s).&nbsp;This is&nbsp;where the chemical reaction occurs.<br>


Every enzyme is equipt with a 'cleft' in its structure which is complementary to a particular [[Substrate|substrate]]. This is known as the active site. As well as shape, specificity of the active site is developed further via the [[Amino acid|amino acid]] R-Groups&nbsp;within&nbsp;the&nbsp;site. These groups will interact specifically with the substrate molecule(s) <ref>https://docs.google.com/viewer?a=v&amp;q=cache:Tn0x9PalpIkJ:www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf+enzyme+substrate+complex&amp;hl=en&amp;gl=uk&amp;pid=bl&amp;srcid=ADGEESinQz_Nw7C9lQYmplfliEswGAdvSyRx0aqr91j0UUF_y51PABTPgupe6supWcqudck5HgOKFbgnmCU-1rzngFubqzwP8zOZWQoUlM5Yxc3x0R_eMQMYqT7BxkkSqnb5M22ygi3f&amp;sig=AHIEtbSTALob3Xfcnm8CLj2rhZKL97OWwA</ref>.&nbsp;The ES&nbsp;complex is the state in which the active site of the enzyme is [[Non-covalently bound|non-covalently bound]] to the substrate [[Molecule|molecule]](s).&nbsp;This is&nbsp;where the chemical reaction occurs.<br>


<br>


ENZYME&nbsp;+&nbsp;SUBSTRATE&nbsp;-&gt; ENZYME SUBSTRATE COMPLEX -&gt; ENZYME&nbsp;+ PRODUCT&nbsp;  
ENZYME&nbsp;+&nbsp;SUBSTRATE&nbsp;-&gt; ENZYME SUBSTRATE COMPLEX -&gt; ENZYME&nbsp;+ PRODUCT&nbsp;  
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<br>  
<br>  


The following is a useful video demonstrating&nbsp;the formation of an Enzyme Substrate Complex:&nbsp;[http://www.youtube.com/watch?v=Tn7HJphCBgc www.youtube.com/watch]
The following is a useful video demonstrating&nbsp;the formation of an Enzyme Substrate Complex:&nbsp;[http://www.youtube.com/watch?v=Tn7HJphCBgc www.youtube.com/watch]  
 
=== References ===
 
<references />

Revision as of 18:46, 25 October 2012

Enzyme-Substrate (ES) complexes are formed during enzyme catalysed chemical reactions.

Every enzyme is equipt with a 'cleft' in its structure which is complementary to a particular substrate. This is known as the active site. As well as shape, specificity of the active site is developed further via the amino acid R-Groups within the site. These groups will interact specifically with the substrate molecule(s) [1]. The ES complex is the state in which the active site of the enzyme is non-covalently bound to the substrate molecule(s). This is where the chemical reaction occurs.


ENZYME + SUBSTRATE -> ENZYME SUBSTRATE COMPLEX -> ENZYME + PRODUCT 


The following is a useful video demonstrating the formation of an Enzyme Substrate Complex: www.youtube.com/watch

References

  1. ↑ https://docs.google.com/viewer?a=v&q=cache:Tn0x9PalpIkJ:www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf+enzyme+substrate+complex&hl=en&gl=uk&pid=bl&srcid=ADGEESinQz_Nw7C9lQYmplfliEswGAdvSyRx0aqr91j0UUF_y51PABTPgupe6supWcqudck5HgOKFbgnmCU-1rzngFubqzwP8zOZWQoUlM5Yxc3x0R_eMQMYqT7BxkkSqnb5M22ygi3f&sig=AHIEtbSTALob3Xfcnm8CLj2rhZKL97OWwA
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