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Naproxen is a [https://teaching.ncl.ac.uk/bms/wiki/index.php/ANTI-INFLAMMATORY_DRUGS non-steroidal anti-inflammatory drug] (NSAID)<references />. it is an [https://teaching.ncl.ac.uk/bms/wiki/index.php/Analgesic analgesic] drug<references /> used to reduce pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, menstrual cramps and gout. It is also sometimes used in the treatment of Paget's disease of bone and Bartter syndrome<references />. A side effect of this drug, when taken orally, is intestinal ulceration and bleeding<references />.  
Naproxen is a non-steroidal [[anti-inflammatory drug (NSAID)|anti-inflammatory drug (NSAID)]]&nbsp;<ref>Bond A.D. et al(2014), "Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system.", 1(5):328-337</ref>. it is an analgesic drug&nbsp;<ref>Giménez M et al, (2014), "Naproxen Effects on Brain Response to Painful Pressure Stimulation in Patients with Knee Osteoarthritis: A Double-blind, Randomized, Placebo-controlled, Single-dose Study", The Journal of Rheumatology [online], 41. Available at: http://www.ncbi.nlm.nih.gov/pubmed/erm=Naproxen+Effects+on+Brain+Response+to+Painful+Pressure+Stimulation+in+Patients+with+Knee+Osteoarthritis%3A+A+Double-blind%2C+Randomized%2C+Placebo-controlled%2C+Single-dose+Study [accessed 20.10.2014]</ref>&nbsp;used to reduce pain and inflammation in conditions such as osteoarthritis, [[rheumatoid arthritis|rheumatoid arthritis]], menstrual cramps and gout. It is also sometimes used in the treatment of [[Paget's disease|Paget's disease]] of bone and Bartter syndrome&nbsp;<ref>National Institute of Health (2014) Naproxen. Available at: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a681029.html (last accessed 20.10.14)</ref>. A side effect of this drug, when taken orally, is intestinal ulceration and bleeding&nbsp;<ref>Blackler, R.W. et al (2014), "Hydrogen Sulfide Protects Against NSAID-Enteropathy Through Modulation of Bile and the Microbiota", British Journal of Pharmacology [online] 171. Available at: http://onlinelibrary.wiley.com/doi/10.1111/bph.12961/abstract [accessed 20.10.2014]</ref>.  


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<span style="font-size: 18px; font-weight: bold; line-height: 1.5em; background-color: initial;">References</span>  


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1. Bond A.D. et al(2014), "Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system.", 1(5):328-337
 
2. Giménez M et al, (2014), "Naproxen Effects on Brain Response to Painful Pressure Stimulation in Patients with Knee Osteoarthritis: A Double-blind, Randomized, Placebo-controlled, Single-dose Study", The Journal of Rheumatology [online], 41. Available at: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Naproxen+Effects+on+Brain+Response+to+Painful+Pressure+Stimulation+in+Patients+with+Knee+Osteoarthritis%3A+A+Double-blind%2C+Randomized%2C+Placebo-controlled%2C+Single-dose+Study http://www.ncbi.nlm.nih.gov/pubmed/?term=Naproxen+Effects+on+Brain+Response+to+Painful+Pressure+Stimulation+in+Patients+with+Knee+Osteoarthritis%3A+A+Double-blind%2C+Randomized%2C+Placebo-controlled%2C+Single-dose+Study] [accessed 20.10.2014]
 
3. National Institute of Health (2014) Naproxen. Available at: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a681029.html (last accessed 20.10.14)
 
4. Blackler, R.W. et al (2014), "Hydrogen Sulfide Protects Against NSAID-Enteropathy Through Modulation of Bile and the Microbiota", British Journal of Pharmacology [online] 171. Available at: http://onlinelibrary.wiley.com/doi/10.1111/bph.12961/abstract [accessed 20.10.2014]

Latest revision as of 01:25, 24 October 2014

Naproxen is a non-steroidal anti-inflammatory drug (NSAID) [1]. it is an analgesic drug [2] used to reduce pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, menstrual cramps and gout. It is also sometimes used in the treatment of Paget's disease of bone and Bartter syndrome [3]. A side effect of this drug, when taken orally, is intestinal ulceration and bleeding [4].

References

  1. ↑ Bond A.D. et al(2014), "Structural basis for the transformation pathways of the sodium naproxen anhydrate-hydrate system.", 1(5):328-337
  2. ↑ Giménez M et al, (2014), "Naproxen Effects on Brain Response to Painful Pressure Stimulation in Patients with Knee Osteoarthritis: A Double-blind, Randomized, Placebo-controlled, Single-dose Study", The Journal of Rheumatology [online], 41. Available at: http://www.ncbi.nlm.nih.gov/pubmed/erm=Naproxen+Effects+on+Brain+Response+to+Painful+Pressure+Stimulation+in+Patients+with+Knee+Osteoarthritis%3A+A+Double-blind%2C+Randomized%2C+Placebo-controlled%2C+Single-dose+Study [accessed 20.10.2014]
  3. ↑ National Institute of Health (2014) Naproxen. Available at: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a681029.html (last accessed 20.10.14)
  4. ↑ Blackler, R.W. et al (2014), "Hydrogen Sulfide Protects Against NSAID-Enteropathy Through Modulation of Bile and the Microbiota", British Journal of Pharmacology [online] 171. Available at: http://onlinelibrary.wiley.com/doi/10.1111/bph.12961/abstract [accessed 20.10.2014]
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