Inner nuclear membrane: Difference between revisions
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Inner nuclear membranes are part of the [[ | Inner nuclear membranes are part of the [[Nuclear envelope|nuclear envelope]] in cells which contain the [[DNA|DNA]] of [[Eukaryotes|eukaryotes]] (cells with a membrane [[Nucleus|nucleus]]). The membrane is made of two layers, outer and inner, joined in a continuous loop with pores allowing for the transfer of substances into and out of the nucleus. The inner and outer membranes differ in that they do not consist of the same proteins<ref>Alberts et al., (2009) Molecular Biology of the Cell, 5th ed.</ref>. | ||
The inner nuclear membrane contains proteins specific to its function, allowing for structural organisation and support of the [[Organelle|organelle]]. Some of these [[Protein|proteins]] include [[Nurim|nurim]], [[MAN 1|MAN 1]], [[Lamin B receptor|lamin B receptor]] (LBR), [[Lamina-associated polypeptide (LAP) 1|lamina-associated polypeptide (LAP) 1]], [[Lamina-associated polypeptide (LAP) 2|LAP2]] and [[Emerin|emerin]] which are important in the attachment of [[Chromatin|chromatin]] and [[Nuclear lamins|lamins]]<ref>Homer L. et al (2001) Inner nuclear membrane proteins: functions and targeting, Cell Mol Life Sci., 58(12-13):1741-7</ref>. The lamina, made up of nuclear lamins, is a lattice of protein inside the nucleus and is vital in its support<ref>Alberts et. al, 2009, Molecular Biology of the Cell, 5th ed.</ref>. | |||
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Latest revision as of 14:12, 29 November 2018
Inner nuclear membranes are part of the nuclear envelope in cells which contain the DNA of eukaryotes (cells with a membrane nucleus). The membrane is made of two layers, outer and inner, joined in a continuous loop with pores allowing for the transfer of substances into and out of the nucleus. The inner and outer membranes differ in that they do not consist of the same proteins[1].
The inner nuclear membrane contains proteins specific to its function, allowing for structural organisation and support of the organelle. Some of these proteins include nurim, MAN 1, lamin B receptor (LBR), lamina-associated polypeptide (LAP) 1, LAP2 and emerin which are important in the attachment of chromatin and lamins[2]. The lamina, made up of nuclear lamins, is a lattice of protein inside the nucleus and is vital in its support[3].