Deamination: Difference between revisions
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Deamination is the process that removes an [[Amine]] group from a molecule.<br> | Deamination is the process that removes an [[Amine]] group from a molecule.<br> | ||
[[Deaminases]] are [[enzymes]] that [[catalyse]] this reaction. | |||
Deamination of [[Nucleotide]] Bases: | Deamination of [[Nucleotide]] Bases: | ||
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*Removing an amine group from a base can alter its structure. | *Removing an amine group from a base can alter its structure. | ||
*Deamination of [[Cytosine]] transforms it into [[Uracil]] | *Deamination of [[Cytosine]] transforms it into [[Uracil]] | ||
*[[Uracil|Uracil]]Deamination of [[Adenine]] transforms it into [[Hypoxanthine]] | *[[Uracil|Uracil]] Deamination of [[Adenine]] transforms it into [[Hypoxanthine]] | ||
*[[Hypoxanthine|Hypoxanthine]]Deamination of [[Guanine]] transforms it into [[Thymine]] <ref>http://www.bath.ac.uk/bio-sci/oer/DNA%20damage%20deamination.htm</ref> | *[[Hypoxanthine|Hypoxanthine]] Deamination of [[Guanine]] transforms it into [[Thymine]] <ref>http://www.bath.ac.uk/bio-sci/oer/DNA%20damage%20deamination.htm</ref> | ||
*Deamination of [[Amino Acids]]: | *Deamination of [[Amino Acids]]: | ||
Latest revision as of 13:59, 23 October 2015
Deamination is the process that removes an Amine group from a molecule.
Deaminases are enzymes that catalyse this reaction.
Deamination of Nucleotide Bases:
- Removing an amine group from a base can alter its structure.
- Deamination of Cytosine transforms it into Uracil
- Uracil Deamination of Adenine transforms it into Hypoxanthine
- Hypoxanthine Deamination of Guanine transforms it into Thymine [1]
- Deamination of Amino Acids:
Involves removing NH2 (amino group) from an amino acid and forming ammonia (NH3) by reacting the amino acid with oxygen [2].
The organic acid containing an oxygen with a double bond is usually respired.
Ammonia is a toxic substance to the body and is converted quickly into urea which is less harmful. The kidneys remove urea from the body.
References
- ↑ http://www.bath.ac.uk/bio-sci/oer/DNA%20damage%20deamination.htm
- ↑ Boyle M. (2008) Biology, 3rd edition, London: Collins. p242