Keratinocytes: Difference between revisions
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Epidermal keratinocytes (skin cells) are highly specialized [[ | Epidermal keratinocytes (skin cells) are highly specialized [[Epitheial Cells|epithelial cells designed]] to perform a very specific function, separation of the organism from its environment. To accomplish this, the cells synthesize precursors and assemble them into two distinct structures, the cornified envelope and keratin intermediate filaments. The [[Intermediate filaments|intermediate filaments are]] assembled from keratin monomers and the cornified envelope is assembled from a protein called involucrin and several other proteins. Expression of involucrin and the keratins genes are regulated as a function of the stage of keratinocyte differentiation and by various external agents such as [[Calcium|calcium and]] [[Vitamin A|vitamin A]]<ref name="null">Environmental Health Perspectives 1989 Vol. 80, pp. 109-116, 1989 Richard Leon Eckert* and Ellen Anne Rorket</ref>. | ||
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Latest revision as of 17:42, 24 October 2017
Epidermal keratinocytes (skin cells) are highly specialized epithelial cells designed to perform a very specific function, separation of the organism from its environment. To accomplish this, the cells synthesize precursors and assemble them into two distinct structures, the cornified envelope and keratin intermediate filaments. The intermediate filaments are assembled from keratin monomers and the cornified envelope is assembled from a protein called involucrin and several other proteins. Expression of involucrin and the keratins genes are regulated as a function of the stage of keratinocyte differentiation and by various external agents such as calcium and vitamin A[1].
References
- ↑ Environmental Health Perspectives 1989 Vol. 80, pp. 109-116, 1989 Richard Leon Eckert* and Ellen Anne Rorket