Ligands: Difference between revisions
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In chemical terms, ligands are ions or molecules which bind to a central metal ion. The ligands are [[Electron|electron]] donors, meaning they have free electrons by which they can form [[Dative covalent bond|dative covalent bonds]] with the central metal ion. A common example of a ligand is [[Water|water]], which has two lone pairs of electrons on the [[Oxygen|oxygen]] atom which it is free to donate<ref>"Ligands" Chemicool dictionary. 12/4/2017 &lt;//www.chemicool.com/definition/ligand.html&gt;</ref>. In biology however, we mainly refer protein bound ligands. These are molecules which simply form a set of weak non covalent bonds with a protein. Collectively, these interactions bind the protein and substrate together<ref>Molecular biology of the cell. Fifth edition. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter. 2008.</ref>. | In chemical terms, ligands are [[ions|ions]] or [[molecules|molecules]] which bind to a central [[metal ion|metal ion]]. The ligands are [[Electron|electron]] donors, meaning they have free [[electrons|electrons]] by which they can form [[Dative covalent bond|dative covalent bonds]] with the central metal ion. A common example of a ligand is [[Water|water]], which has two lone pairs of electrons on the [[Oxygen|oxygen]] atom which it is free to donate<ref>"Ligands" Chemicool dictionary. 12/4/2017 &amp;amp;lt;//www.chemicool.com/definition/ligand.html&amp;amp;gt;</ref>. In biology, however, we mainly refer protein-bound ligands. These are molecules which simply form a set of weak non-covalent bonds with a protein. Collectively, these interactions bind the protein and substrate together<ref>Molecular biology of the cell. Fifth edition. B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter. 2008.</ref>. | ||
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Latest revision as of 20:38, 11 December 2017
In chemical terms, ligands are ions or molecules which bind to a central metal ion. The ligands are electron donors, meaning they have free electrons by which they can form dative covalent bonds with the central metal ion. A common example of a ligand is water, which has two lone pairs of electrons on the oxygen atom which it is free to donate[1]. In biology, however, we mainly refer protein-bound ligands. These are molecules which simply form a set of weak non-covalent bonds with a protein. Collectively, these interactions bind the protein and substrate together[2].