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Created page with "The CLIP protein stands for class II-associated invarient chain peptide and it plays a crucial role in the assembly of [[MHC_Molecules|MHC class I..." |
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The CLIP protein stands for class II-associated [[ | The CLIP protein stands for class II-associated [[Invarient chain|invarient chain]] [[Peptide|peptide]] and it plays a crucial role in the assembly of [[MHC Molecules|MHC class II molecules]]. The CLIP protein is a part of the [[Invarient chain|invarient chain]] and it stops the MHC complex binding with [[Self peptides|self-peptides]] in the endosome called the MHC II compartment. Therefore, it allows foreign peptides to bind to the complex and these antigens can then be presented by this [[Antigen presenting cells|antigen presenting cell]] once the [[Endosome|endosome]] has been transported to the [[Cell membrane|membrane]] of the cell creating a chain of events happening in the [[Immune system|immune system]]. |
Latest revision as of 20:35, 22 October 2018
The CLIP protein stands for class II-associated invarient chain peptide and it plays a crucial role in the assembly of MHC class II molecules. The CLIP protein is a part of the invarient chain and it stops the MHC complex binding with self-peptides in the endosome called the MHC II compartment. Therefore, it allows foreign peptides to bind to the complex and these antigens can then be presented by this antigen presenting cell once the endosome has been transported to the membrane of the cell creating a chain of events happening in the immune system.