MHC Molecules

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Major Histocompatibility Complex (MHC) bind peptide fragments from pathogens, and present them on the cell surface to be detected by T cells [1]. There are 2 types of MHC Molecule: Class 1 MHC and Class 2 MHC:

MHC Class 1

MHC Class 2

References

  1. Murphy K. Weaver C. Janeway's Immunobiology. 9th Edition. Garland Science, Taylor and Francis Group. New York and London. 2016.
  2. Mayer G, Nyland J. Major Histocompatibility Complex(MHC)and T-cell receptors - role in immune response. 2017 [cited 19.10.17]. Available from: http://www.microbiologybook.org/bowers/mhc.htm
  3. Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 6th Ed, Abingdon: Garland Science, Taylor and; Francis Group. 2015.
  4. British Science for Immunology, Cells, CD8+ T Cells, Erika Wissinger
  5. Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 6th Ed, Abingdon: Garland Science, Taylor and; Francis Group. 2015.
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