Na+/K+ ATPase pump: Difference between revisions
No edit summary |
No edit summary |
||
| (One intermediate revision by one other user not shown) | |||
| Line 1: | Line 1: | ||
The Na<sup>+</sup>/K<sup>+</sup> ATPase pump is a pump found in the membrane of animal cell which uses the hydrolysis of [[ATP|ATP]] to pump 3Na<sup>+</sup> out of the cell and 2K<sup>+</sup> into the [[Cell|cell]]. It is a primary active transport and belongs to the family of [[P-type ATPases|P-type ATPases]]. It regulates the [[Osmolarity|osmolarity]] of the [[Cytosol|cytosol]] by controlling the solute concentration inside the cell <ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P(2008). Molecular Biology of the Cell. Garland Science. Fifth Edition</ref>. | The Na<sup>+</sup>/K<sup>+</sup> ATPase pump is a pump found in the membrane of animal cell which uses the hydrolysis of [[ATP|ATP]] to pump 3Na<sup>+</sup> out of the cell and 2K<sup>+</sup> into the [[Cell|cell]]. It is a primary active transport and belongs to the family of [[P-type ATPases|P-type ATPases]]. It regulates the [[Osmolarity|osmolarity]] of the [[Cytosol|cytosol]] by controlling the solute concentration inside the cell<ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P(2008). Molecular Biology of the Cell. Garland Science. Fifth Edition</ref>.The main function of the N+/K+ ATPase pump is to maintain resting potential so that the cells will be keeping in a state of a low concentration of sodium ions and high levels of potassium ions within the cell (intracellular). | ||
The sodium-[[Na+/K+_ATPase_pump|potassium]] pump is an [[Antiporter|antiporter]] transport [[Protein|protein]] | The sodium-[[Na+/K+_ATPase_pump|potassium]] pump is an [[Antiporter|antiporter]] transport [[Protein|protein]]<ref>Alberts et al. 2008, pg 661</ref>. This pump is responsible for the usage of almost 30% of the body's [[ATP|ATP]], this is due to 1 molecule of [[ATP|ATP]] being hydrolysed as three molecules of [[Sodium|Na]]<sup>[[Sodium|+]]</sup> are pumped out of the cell and two molecules of [[Potassium|K]]<sup>[[Potassium|+]]</sup> are pumped into the cell<ref>Alberts et al. 2008, pg 661</ref>. The sodium-potassium pump is a very important protein in our cell membranes. The pump can be used to generate [[ATP|ATP]] when supplies are low by working in the opposite way<ref>Alberts et al. 2008, pg 662</ref>. The pump is also used to control the osmolarity of the [[Cell|cell]], by pumping the [[Sodium|Na]]<sup>[[Sodium|+]]</sup> out that have diffused into the cell down their high [[Electrochemical gradient|electrochemical gradient]] the cell can be kept at osmotic equilibrium<ref>Alberts et al. 2008 pg 663</ref>. The pump plays a large role in nerve cells and initiating [[Action potential|action potentials]]. [[Action potential|Action potentials]] could not occur without these cells. They initiate the first part of the depolarisation before the voltage-gated channels come into play. The sodium-potassium pumps also recover the axon to its resting state of -60mV after an action potential has passed. | ||
=== References === | === References === | ||
<references /> | <references /> | ||
Latest revision as of 06:09, 24 October 2018
The Na+/K+ ATPase pump is a pump found in the membrane of animal cell which uses the hydrolysis of ATP to pump 3Na+ out of the cell and 2K+ into the cell. It is a primary active transport and belongs to the family of P-type ATPases. It regulates the osmolarity of the cytosol by controlling the solute concentration inside the cell[1].The main function of the N+/K+ ATPase pump is to maintain resting potential so that the cells will be keeping in a state of a low concentration of sodium ions and high levels of potassium ions within the cell (intracellular).
The sodium-potassium pump is an antiporter transport protein[2]. This pump is responsible for the usage of almost 30% of the body's ATP, this is due to 1 molecule of ATP being hydrolysed as three molecules of Na+ are pumped out of the cell and two molecules of K+ are pumped into the cell[3]. The sodium-potassium pump is a very important protein in our cell membranes. The pump can be used to generate ATP when supplies are low by working in the opposite way[4]. The pump is also used to control the osmolarity of the cell, by pumping the Na+ out that have diffused into the cell down their high electrochemical gradient the cell can be kept at osmotic equilibrium[5]. The pump plays a large role in nerve cells and initiating action potentials. Action potentials could not occur without these cells. They initiate the first part of the depolarisation before the voltage-gated channels come into play. The sodium-potassium pumps also recover the axon to its resting state of -60mV after an action potential has passed.