Single-strand binding protein: Difference between revisions
Jump to navigation
Jump to search
Created page with "A single-strand binding protein is able to bind to single stranded DNA during the process of DNA semi-conservative replication. It ..." |
Cleared up reference formatting |
||
| (3 intermediate revisions by 3 users not shown) | |||
| Line 1: | Line 1: | ||
A single-strand binding protein is able to bind to single stranded [[DNA|DNA]] during the process of DNA [[Semi- | A single-strand binding protein is able to bind to single stranded [[DNA|DNA]] during the process of DNA [[Semi-conservative replication|semi-conservative replication.]] It prevents the two DNA strands that are being used as templates reannealing to one another<ref>N. Campbell.(2005) Biology, 7th edition, USA: Pearson Education Inc</ref>. | ||
<references /> | Single-strand binding (SSB) proteins work together with DNA helicase to unwind the helix and expose the template bases. SSB proteins assist helicase by stabilising the unwound, single-strand conformation. They also prevent short hairpin helices from forming by straightening out single-stranded DNA on the lagging strand<ref>Alberts, B. (2008). Molecular biology of the cell. New York: Garland Science. Pg 273.</ref>. SSB binds ssDNA tightly since it has a greater affinity for ssDNA than dsDNA. | ||
=== References === | |||
<references /><br> | |||
Latest revision as of 10:53, 19 November 2018
A single-strand binding protein is able to bind to single stranded DNA during the process of DNA semi-conservative replication. It prevents the two DNA strands that are being used as templates reannealing to one another[1].
Single-strand binding (SSB) proteins work together with DNA helicase to unwind the helix and expose the template bases. SSB proteins assist helicase by stabilising the unwound, single-strand conformation. They also prevent short hairpin helices from forming by straightening out single-stranded DNA on the lagging strand[2]. SSB binds ssDNA tightly since it has a greater affinity for ssDNA than dsDNA.