Deamination: Difference between revisions
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Involves removing NH<sub>2</sub> ([[ | Deamination is the process that removes an [[Amine]] group from a molecule.<br> | ||
[[Deaminases]] are [[enzymes]] that [[catalyse]] this reaction. | |||
Deamination of [[Nucleotide]] Bases: | |||
*Removing an amine group from a base can alter its structure. | |||
*Deamination of [[Cytosine]] transforms it into [[Uracil]] | |||
*[[Uracil|Uracil]] Deamination of [[Adenine]] transforms it into [[Hypoxanthine]] | |||
*[[Hypoxanthine|Hypoxanthine]] Deamination of [[Guanine]] transforms it into [[Thymine]] <ref>http://www.bath.ac.uk/bio-sci/oer/DNA%20damage%20deamination.htm</ref> | |||
*Deamination of [[Amino Acids]]: | |||
Involves removing NH<sub>2</sub> ([[Amino group|amino group]]) from an amino acid and forming [[Ammonia|ammonia]] (NH<sub>3</sub>) by reacting the amino acid with [[Oxygen|oxygen]] <ref>Boyle M. (2008) Biology, 3rd edition, London: Collins. p242</ref>. | |||
The organic acid containing an oxygen with a double bond is usually respired. | The organic acid containing an oxygen with a double bond is usually respired. | ||
Ammonia is a toxic substance to the body and is converted quickly into urea which is less harmful. The [[ | Ammonia is a toxic substance to the body and is converted quickly into urea which is less harmful. The [[Kidneys|kidneys]] remove [[Urea|urea]] from the body.<br> | ||
=== References === | === References === | ||
<references /> | <references /> | ||
Latest revision as of 13:59, 23 October 2015
Deamination is the process that removes an Amine group from a molecule.
Deaminases are enzymes that catalyse this reaction.
Deamination of Nucleotide Bases:
- Removing an amine group from a base can alter its structure.
- Deamination of Cytosine transforms it into Uracil
- Uracil Deamination of Adenine transforms it into Hypoxanthine
- Hypoxanthine Deamination of Guanine transforms it into Thymine [1]
- Deamination of Amino Acids:
Involves removing NH2 (amino group) from an amino acid and forming ammonia (NH3) by reacting the amino acid with oxygen [2].
The organic acid containing an oxygen with a double bond is usually respired.
Ammonia is a toxic substance to the body and is converted quickly into urea which is less harmful. The kidneys remove urea from the body.
References
- ↑ http://www.bath.ac.uk/bio-sci/oer/DNA%20damage%20deamination.htm
- ↑ Boyle M. (2008) Biology, 3rd edition, London: Collins. p242