Reiji Okazaki: Difference between revisions
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Reiji [[Okazaki|Okazaki]] was the scientist who explained how both strands of [[DNA|DNA]] were replicated when all [[DNA Polymerase|DNA polymerases]] worked in the 5'-3' direction only. Okazaki found that the 3'-5' daughter strand was being synthesised in small fragments of around 1000 [[Nucleotides|nucleotides]] in the 5'-3' direction. This was know as the lagging strand and the fragments called Okazaki fragments. It is the [[DNA ligase|DNA ligase]] which joins the Okazaki fragments to give a complete strand of DNA<ref>Biochemistry, 7th edition, Berg, Tymoczko, Stryer, 853</ref>. | |||
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Latest revision as of 16:06, 16 November 2018
Reiji Okazaki was the scientist who explained how both strands of DNA were replicated when all DNA polymerases worked in the 5'-3' direction only. Okazaki found that the 3'-5' daughter strand was being synthesised in small fragments of around 1000 nucleotides in the 5'-3' direction. This was know as the lagging strand and the fragments called Okazaki fragments. It is the DNA ligase which joins the Okazaki fragments to give a complete strand of DNA[1].
References
- ↑ Biochemistry, 7th edition, Berg, Tymoczko, Stryer, 853