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Ligation, in molecular biology, is the process where either 2 [[DNA|DNA]] or [[RNA|RNA]] strands are joined together by an [[Enzyme|enzyme]] called [[Ligase|ligase]]. Ligation occurs during the cloning of DNA or during processes such as transformation of a [[Plasmid|plasmid]]. Ligation is important in biotechnology as it can allow for the detection and determination of changes in RNA sequences<ref>Nilsson et al (2001) "RNA-templated DNA ligation for transcript analysis" Nucleic acid research.</ref>. | |||
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Latest revision as of 14:38, 30 November 2016
Ligation, in molecular biology, is the process where either 2 DNA or RNA strands are joined together by an enzyme called ligase. Ligation occurs during the cloning of DNA or during processes such as transformation of a plasmid. Ligation is important in biotechnology as it can allow for the detection and determination of changes in RNA sequences[1].
References
- ↑ Nilsson et al (2001) "RNA-templated DNA ligation for transcript analysis" Nucleic acid research.