Single stranded binding protein: Difference between revisions

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The single stranded binding protein also known as SSBP is a protein that holds single stranded DNA strands and prevents them from reannealing after they have been unwinded by the DNA helicase.  
Single stranded binding proteins (SSBs) are also known as helix-destabilising proteins<ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 5th Ed, New York: Garland Science. 2008.</ref>. They bind to exposed single stranded DNA during [[Dna replication|DNA replication]] which prevents&nbsp;the 2 strands from re-annealing&nbsp;after they have been unwound by [[DNA helicase|DNA helicase]]<ref>Abedon ST, Biologyaspoetry. Single-stranded binding protein. 2016.fckLRhttp://www.biologyaspoetry.com/terms/single_strand_binding_protein.html</ref>. They also prevent interactions within the single strand of DNA such as the formation of hairpin loops<ref>Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 5th Ed, New York: Garland Science. 2008.</ref>.<br>


http://www.biologyaspoetry.com/terms/single_strand_binding_protein.html
=== References  ===
 
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Latest revision as of 20:31, 5 December 2017

Single stranded binding proteins (SSBs) are also known as helix-destabilising proteins[1]. They bind to exposed single stranded DNA during DNA replication which prevents the 2 strands from re-annealing after they have been unwound by DNA helicase[2]. They also prevent interactions within the single strand of DNA such as the formation of hairpin loops[3].

References

  1. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 5th Ed, New York: Garland Science. 2008.
  2. Abedon ST, Biologyaspoetry. Single-stranded binding protein. 2016.fckLRhttp://www.biologyaspoetry.com/terms/single_strand_binding_protein.html
  3. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 5th Ed, New York: Garland Science. 2008.