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| <span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">Aspartic
| | Aspartic acid, also known as aspartate, is an [[Amino acid|amino acid]] with an acidic side chain. At normal [[PH|pH]] it usually carries a negative charge. This is due to a missing proton from the -COOH ([[Carboxylic acid|carboxylic acid]]) group.<br>It is coded for by the the three letter code Asp and the one letter code D <ref>Berg, Tymoczko and Stryer. (2006) Biochemistry, 6th edition, New York: WH Freeman</ref>. |
| acid, also known as aspartate, is an </span>[https://teaching.ncl.ac.uk/bms/wiki/extensions/FCKeditor/fckeditor/editor/Amino%20acid <span style="color:#0013A9">amino acid</span>]<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;"> with an acidic side chain. At | |
| normal </span>[https://teaching.ncl.ac.uk/bms/wiki/extensions/FCKeditor/fckeditor/editor/PH <span style="color:#0013A9">pH</span>]<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;"> it usually carries a negative charge. This | |
| is due to a missing proton from the -COOH (</span>[https://teaching.ncl.ac.uk/bms/wiki/extensions/FCKeditor/fckeditor/editor/Carboxylic%20acid <span style="color:#0013A9">carboxylic acid</span>]<span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">) group. Aspartic acid has the | |
| chemical formula HOOCCH(NH</span><sub style="font-family: Helvetica; line-height: 1.5em; text-align: justify;">2</sub><span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">)CH</span><sub style="font-family: Helvetica; line-height: 1.5em; text-align: justify;">2. </sub><span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;">Aspartic acid along
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| with glutamic acid is the only acidic amino acid with a pk</span><sub style="font-family: Helvetica; line-height: 1.5em; text-align: justify;">a</sub><span style="font-family: Helvetica; font-size: 13pt; line-height: 1.5em; text-align: justify;"> of 3.86. T</span><span lang="EN-US" style="font-size:13.0pt;font-family:Helvetica;mso-bidi-font-family:Helvetica">he
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| amino acid has both ‘L’ and ‘D’ isomers, and the </span><span lang="EN-US" style="font-size:11.0pt;font-family:Helvetica;mso-bidi-font-family:Helvetica">L</span><span lang="EN-US" style="font-size:13.0pt;font-family:Helvetica;mso-bidi-font-family: Helvetica">-isomer of aspartate is one of the 22 [http://en.wikipedia.org/wiki/Proteinogenic_amino_acid <span style="color:#0013A9">proteinogenic</span>] amino acids (those that are the building blocks of proteins). Most chemical syntheses will produce a ‘DL-aspartic acid’ which is a racemic mixture.</span>
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| <span lang="EN-US" style="font-size: 13.0pt;font-family:Helvetica;mso-bidi-font-family:Helvetica">It is coded for by
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| the three letter code Asp and the one letter code D.</span><br>
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| <references />academics.keene.edu/rblatchly/Chem220/hand/npaa/aawpka.htm <br>
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Revision as of 02:54, 1 December 2013
Aspartic acid, also known as aspartate, is an amino acid with an acidic side chain. At normal pH it usually carries a negative charge. This is due to a missing proton from the -COOH (carboxylic acid) group.
It is coded for by the the three letter code Asp and the one letter code D [1].
Reference
- ↑ Berg, Tymoczko and Stryer. (2006) Biochemistry, 6th edition, New York: WH Freeman