Adaptor proteins: Difference between revisions
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Adaptor proteins are [[Cell signalling|cell signalling proteins]], which enable the continued transduction of a cell signal<ref>Johnson, A et al . (2008). Mechanisms of Cell Communication. In: Schanck, D. and Masson, S. Molecular Biology of the Cell. 5th ed. New York: Garland science . p879-964.</ref>. These proteins usually bridge a gap between two other proteins in the signalling pathway allowing the continued propagation of the signal to give rise to a cellular response<ref>Flynn, D. (2001). Adaptor proteins. Oncogene . 20 (44), p6270-6272.</ref>.<br> | Adaptor proteins are [[Cell signalling|cell signalling proteins]], which enable the continued transduction of a cell signal<ref>Johnson, A et al . (2008). Mechanisms of Cell Communication. In: Schanck, D. and Masson, S. Molecular Biology of the Cell. 5th ed. New York: Garland science . p879-964.</ref>. These proteins usually bridge a gap between two other proteins in the signalling pathway allowing the continued propagation of the signal to give rise to a cellular response<ref>Flynn, D. (2001). Adaptor proteins. Oncogene . 20 (44), p6270-6272.</ref>.<br> | ||
=== | An example of an adaptor protein would be in the Grb-2 adaptor protein that bridges the gap between the [https://teaching.ncl.ac.uk/bms/wiki/index.php/Ras Ras] GEF and phosphorylated tyrosines in the [https://teaching.ncl.ac.uk/bms/wiki/index.php/Ras Ras] signalling pathwa<sup></sup>y<ref>http://www.sabiosciences.com/pathway.php?sn=Ras_Pathway</ref> | ||
=== References === | |||
<references /> | <references /> | ||
Revision as of 17:35, 3 December 2017
Adaptor proteins are cell signalling proteins, which enable the continued transduction of a cell signal[1]. These proteins usually bridge a gap between two other proteins in the signalling pathway allowing the continued propagation of the signal to give rise to a cellular response[2].
An example of an adaptor protein would be in the Grb-2 adaptor protein that bridges the gap between the Ras GEF and phosphorylated tyrosines in the Ras signalling pathway[3]
References
- ↑ Johnson, A et al . (2008). Mechanisms of Cell Communication. In: Schanck, D. and Masson, S. Molecular Biology of the Cell. 5th ed. New York: Garland science . p879-964.
- ↑ Flynn, D. (2001). Adaptor proteins. Oncogene . 20 (44), p6270-6272.
- ↑ http://www.sabiosciences.com/pathway.php?sn=Ras_Pathway