Adaptor proteins

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Adaptor proteins are cell signalling proteins, which enable the continued transduction of a cell signal[1]. These proteins usually bridge a gap between two other proteins in the signalling pathway allowing the continued propagation of the signal to give rise to a cellular response[2].

An example of an adaptor protein would be in the Grb-2 adaptor protein that bridges the gap between the Ras GEF and phosphorylated tyrosines in the Ras signalling pathway[3] .

References 

  1. Johnson, A et al . (2008). Mechanisms of Cell Communication. In: Schanck, D. and Masson, S. Molecular Biology of the Cell. 5th ed. New York: Garland science . p879-964.
  2. Flynn, D. (2001). Adaptor proteins. Oncogene . 20 (44), p6270-6272.
  3. http://www.sabiosciences.com/pathway.php?sn=Ras_Pathway
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