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Curare is a poison found in the Strychnos toxifera plant used by the South American indigenous tribes. | Curare is a poison found in the ''Strychnos toxifera'' plant used by the South American indigenous tribes. | ||
The main toxin is D-tubocurarine | The main toxin is [[D-tubocurarine|D-tubocurarine]]. | ||
It is a muscle relaxant which binds to the Nicotinic acetylcholine receptors. Curare is a competative antagonist, in which it binds to the sites for the receptor with a higher affinity than that of acetylcholine. | It is a [[Muscle|muscle]] relaxant which binds to the [[Nicotinic acetylcholine receptors|Nicotinic acetylcholine receptors]]. Curare is a [[Competative antagonist|competative antagonist]], in which it binds to the sites for the receptor with a higher affinity than that of [[Acetylcholine|acetylcholine]]. | ||
Curare has been used for its anaestheic properties for many years. Previously the cyclopropane anaesthesia caused severe cardiovascular depression, due to the depth of the anaesthesia caused | Curare has been used for its anaestheic properties for many years. Previously the [[Cyclopropane|cyclopropane]] anaesthesia caused severe cardiovascular depression, due to the depth of the anaesthesia caused <ref>Foldes FF. 2003</ref>. | ||
=== References === | |||
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Revision as of 14:11, 27 November 2010
Curare is a poison found in the Strychnos toxifera plant used by the South American indigenous tribes.
The main toxin is D-tubocurarine.
It is a muscle relaxant which binds to the Nicotinic acetylcholine receptors. Curare is a competative antagonist, in which it binds to the sites for the receptor with a higher affinity than that of acetylcholine.
Curare has been used for its anaestheic properties for many years. Previously the cyclopropane anaesthesia caused severe cardiovascular depression, due to the depth of the anaesthesia caused [1].
References
- ↑ Foldes FF. 2003