Curare is a poison found in the Strychnos toxifera plant used by the South American indigenous tribes.
The main toxin is D-tubocurarine.
It is a muscle relaxant which binds to the Nicotinic acetylcholine receptors. Curare is a competative antagonist, in which it binds to the sites for the receptor with a higher affinity than that of acetylcholine.
- ↑ Foldes FF. 2003