Curare: Difference between revisions
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Curare is a poison found in the ''Strychnos toxifera'' plant used by the South American indigenous tribes. | Curare is a poison found in the ''Strychnos toxifera'' plant used by the South American indigenous tribes. | ||
The main toxin is [[D-tubocurarine|D-tubocurarine]]. | The main toxin is [[D-tubocurarine|D-tubocurarine]]. | ||
It is a [[Muscle|muscle]] relaxant which binds to the [[Nicotinic acetylcholine receptors|Nicotinic acetylcholine receptors]]. Curare is a [[Competative antagonist|competative antagonist]], in which it binds to the sites for the receptor with a higher affinity than that of [[Acetylcholine|acetylcholine]]. | It is a [[Muscle|muscle]] relaxant which binds to the [[Nicotinic acetylcholine receptors|Nicotinic acetylcholine receptors]]. Curare is a [[Competative antagonist|competative antagonist]], in which it binds to the sites for the [[Receptor|receptor]] with a higher affinity than that of [[Acetylcholine|acetylcholine]]. | ||
Curare has been used for its anaestheic properties for many years. Previously the [[Cyclopropane|cyclopropane]] anaesthesia caused severe cardiovascular depression, due to the depth of the anaesthesia caused <ref>Foldes FF. 2003</ref>. | Curare has been used for its anaestheic properties for many years. Previously the [[Cyclopropane|cyclopropane]] anaesthesia caused severe cardiovascular depression, due to the depth of the anaesthesia caused <ref>Foldes FF. 2003</ref>. | ||
=== References === | === References === | ||
<references /> | <references /> | ||
Revision as of 11:33, 14 November 2011
Curare is a poison found in the Strychnos toxifera plant used by the South American indigenous tribes.
The main toxin is D-tubocurarine.
It is a muscle relaxant which binds to the Nicotinic acetylcholine receptors. Curare is a competative antagonist, in which it binds to the sites for the receptor with a higher affinity than that of acetylcholine.
Curare has been used for its anaestheic properties for many years. Previously the cyclopropane anaesthesia caused severe cardiovascular depression, due to the depth of the anaesthesia caused [1].
References
- ↑ Foldes FF. 2003