CpG island: Difference between revisions
Jump to navigation
Jump to search
Created page with "CpG island is a region of DNA with higher than usual CG sequence content. <ref>http://www.everythingbio.com/glos/definition.php?word=CpG+island</ref> ==..." |
No edit summary |
||
| Line 1: | Line 1: | ||
[[ | [[CpG_island|CpG island]] is a region of [[DNA|DNA]] with higher than usual CG sequence content and mostly found in [[Promoter|promoter]] regions. <ref>http://www.everythingbio.com/glos/definition.php?word=CpG+island</ref> Usually unmethylated, CpG islands are important in [[epigenetics|epigenetic ]]control of gene expression. Methylation of these regions can cause [[cancer|cancer]] and other disease states. <ref>Bock C, Paulsen M, Tierling S, Mikeska T, Lengauer T, et al. (2006) CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure. PLoS Genet 2(3): e26. doi:10.1371/journal.pgen.0020026</ref> | ||
<br> | |||
== References == | |||
== References == | |||
<references /> | <references /> | ||
Revision as of 10:14, 15 November 2011
CpG island is a region of DNA with higher than usual CG sequence content and mostly found in promoter regions. [1] Usually unmethylated, CpG islands are important in epigenetic control of gene expression. Methylation of these regions can cause cancer and other disease states. [2]
References
- ↑ http://www.everythingbio.com/glos/definition.php?word=CpG+island
- ↑ Bock C, Paulsen M, Tierling S, Mikeska T, Lengauer T, et al. (2006) CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure. PLoS Genet 2(3): e26. doi:10.1371/journal.pgen.0020026