Enac: Difference between revisions
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Enac is a [[Na+ channel|Na]]<sup>[[Na+ channel|+]]</sup>[[Na+ channel|channel]], it can be mutated and cause [[Liddle Syndrome|Liddle Syndrome]] | Enac is a [[Na+ channel|Na]]<sup>[[Na+ channel|+]]</sup>[[Na+ channel|channel]], it can be mutated and cause [[Liddle Syndrome|Liddle Syndrome]] | ||
ENac is important in [[ | ENac is important in [[Cystic fibrosis|Cystic Fibrosis]] too, usually it is inhibited by the [[CFTR|CFTR]] channel but when the patient has CF ENac loses it's inhibition and lets many Na<sup>+</sup> [[ions|ions]] into the cell - this leads to a higher open state probability for the Na<sup>+</sup> channels in the cell. | ||
Revision as of 17:27, 6 November 2010
Enac is a Na+channel, it can be mutated and cause Liddle Syndrome
ENac is important in Cystic Fibrosis too, usually it is inhibited by the CFTR channel but when the patient has CF ENac loses it's inhibition and lets many Na+ ions into the cell - this leads to a higher open state probability for the Na+ channels in the cell.