ABC Superfamily: Difference between revisions

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The ABC Superfamily stands for ATP Binding Cassette Family. These proteins are invloved in ion transport across the memberane, with members including [[CFTR|CFTR]] AND P-[[P- glycoprotein|Glycoprotein]].
The ABC Superfamily stands for ATP Binding Cassette Family. These proteins are invloved in ion transport across the memberane, with members including [[CFTR|CFTR]] AND P-[[P- glycoprotein|Glycoprotein]]. The standard structure of a member of the ABC is 12 membrane-spanning domains and 2 [[Nucelotide Binding Domain|Nucleotide Binding Domains]] (occassionally referred to as a Nucleotide Folding Domain).

Revision as of 10:53, 11 November 2010

The ABC Superfamily stands for ATP Binding Cassette Family. These proteins are invloved in ion transport across the memberane, with members including CFTR AND P-Glycoprotein. The standard structure of a member of the ABC is 12 membrane-spanning domains and 2 Nucleotide Binding Domains (occassionally referred to as a Nucleotide Folding Domain).