Hypomagnesaemia: Difference between revisions

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Hypomagnesaemia is a condition where the blood magnesium levels are abnormally low, due to electrolyte disturbances.  
Hypomagnesaemia is a condition where the blood magnesium levels are abnormally low, due to electrolyte disturbances.  


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'''Looking at the disease on a cellular level:'''


'''Looking at the disease on a cellular level:'''
Transcellular transport creates an electrical gradient (where the basolateral membrane is negatively charged) for Mg<sup>2+</sup> absorption via the paracellular pathway in the thick ascending Loop of Henle. This then causes magnesiun ions to be excreted in the urine.


Transcellular transport creates an electrical gradient (where the basolateral membrane is negatively charged) for Mg<sup>2+</sup> absorption via the paracellular pathway in the thick ascending Loop of Henle. This then causes magnesiun ions to be excreted in the urine.
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Note that Hypomagnesaemia is not the same as magnesium deficiency, as one can be present without the other.


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'''<u>Symptoms:</u>'''


Note that Hypomagnesaemia is not the same as magnesium deficiency, as one can be present without the other.
'''<u></u>'''- Electrolyte disturbances<br>- Nausea<br>- Vomiting<br>- Muscle Weakness<br>- Neuromuscular Dysfunction<br>- Tachycardia<br>- Cardiac Arrythmias<br>- Kidney Stones<br>- Renal Failure
 


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'''<u>Symptoms:</u>'''
References:  


'''<u></u>'''- Electrolyte disturbances<br>- Nausea<br>- VomitinD<br>- Muscle Weakness<br>- Neuromuscular Dysfunction<br>- Tachycardia<br>- Cardiac Arrythmias<br>- Kidney Stones<br>- Renal Failure
1). http://emedicine.medscape.com/article/2038394-overview#a0104

Revision as of 15:30, 21 October 2012

Hypomagnesaemia is a condition where the blood magnesium levels are abnormally low, due to electrolyte disturbances.


Looking at the disease on a cellular level:

Transcellular transport creates an electrical gradient (where the basolateral membrane is negatively charged) for Mg2+ absorption via the paracellular pathway in the thick ascending Loop of Henle. This then causes magnesiun ions to be excreted in the urine.



Note that Hypomagnesaemia is not the same as magnesium deficiency, as one can be present without the other.


Symptoms:

- Electrolyte disturbances
- Nausea
- Vomiting
- Muscle Weakness
- Neuromuscular Dysfunction
- Tachycardia
- Cardiac Arrythmias
- Kidney Stones
- Renal Failure


References:

1). http://emedicine.medscape.com/article/2038394-overview#a0104