Actin filaments: Difference between revisions
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m Cellular Aspects of Smooth Muscle Function, Carsten M, Cambridge University Press, 2005 |
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Actin filaments are the thinnest of the three | Actin filaments are the thinnest of the three components of the [[Cytoskeleton|cytoskeleton]] in respect to its diameter (measuring 7-8nm in diameter in stained sections of muscle cells) and thus, makes it the most flexible. It is required for the movement on the surface of the [[Cell|cells]] and also to maintain the shape of the [[Cell|cell]]. They are found in cells such as [[Microvilli|microvilli]], [[Filopodia|filopodia]] as well as contractile bundles, the [[Plasma membrane|plasma membrane]] and also [[Muscle cell|muscle cells]]. In some preparations they are arranged in rosettes around myosin filaments; however they are most often gathered into bundles or cables,which are many microns long and often merge or branch and terminate by penetrating into a dense body/dense band. | ||
Actin filament is a polymer made by polymerisation of actin monomers by hydrolysis of [[ATP|ATP]]. The filament is polarised and the monomers are more readily added to the positive side of the filament. And polymerisation is also regulated by different set of binding proteins such as bundle protein, cross linked protein, motor proteins etc. | Actin filament is a polymer made by polymerisation of actin monomers by hydrolysis of [[ATP|ATP]]. The filament is polarised and the monomers are more readily added to the positive side of the filament. And polymerisation is also regulated by different set of binding proteins such as bundle protein, cross linked protein, motor proteins etc. | ||
The actin filament's motor proteins are the myosin. [[Myosin|Myosin]] have a head and a tail, the head binds to the actin filament and the tail is bound to [[Plasma membrane|plasma membrane]], [[ | The actin filament's motor proteins are the myosin. [[Myosin|Myosin]] have a head and a tail, the head binds to the actin filament and the tail is bound to [[Plasma membrane|plasma membrane]], [[Vesicles|vesicles]] and other yosin proteins. The hydrolysis of [[ATP|ATP]] drives the myosin resulting in movement. | ||
Myosin is further divided into [[ | Myosin is further divided into [[Myosin 1|myosin 1]] and [[Myosin 2|myosin 2]]. | ||
Also see [[Actin|actin]] | Also see [[Actin|actin]] | ||
Revision as of 12:30, 24 November 2013
Actin filaments are the thinnest of the three components of the cytoskeleton in respect to its diameter (measuring 7-8nm in diameter in stained sections of muscle cells) and thus, makes it the most flexible. It is required for the movement on the surface of the cells and also to maintain the shape of the cell. They are found in cells such as microvilli, filopodia as well as contractile bundles, the plasma membrane and also muscle cells. In some preparations they are arranged in rosettes around myosin filaments; however they are most often gathered into bundles or cables,which are many microns long and often merge or branch and terminate by penetrating into a dense body/dense band.
Actin filament is a polymer made by polymerisation of actin monomers by hydrolysis of ATP. The filament is polarised and the monomers are more readily added to the positive side of the filament. And polymerisation is also regulated by different set of binding proteins such as bundle protein, cross linked protein, motor proteins etc.
The actin filament's motor proteins are the myosin. Myosin have a head and a tail, the head binds to the actin filament and the tail is bound to plasma membrane, vesicles and other yosin proteins. The hydrolysis of ATP drives the myosin resulting in movement.
Myosin is further divided into myosin 1 and myosin 2.
Also see actin