From The School of Biomedical Sciences Wiki
Jump to navigation
Jump to search
|
|
| Line 1: |
Line 1: |
| Gram-negative refers to a classification of bacteria based upon their cell wall structure. Gram-negative bacteria appear red as a result of [[Gram staining|Gram testing]], whereas [[Gram-positive]] stain purple.<br>
| | See [[Gram_negative|Gram negative]] |
| | |
| <u></u>The structure of the Gram-negative bacterial cell wall is what distinguishes it from Gram-positive bacteria. Gram-negative bacteria contain a much thinner layer of [[Peptidoglycan]] in comparison to a Gram-positive bacterial cell wall. The Gram-negative cell wall consists of a unique outer membrane, containing lipopolysaccharides, murein lipoproteins and porin channels. There is also a periplasmic space between the peptidoglycan cell wall, and the cell membrane.
| |
| | |
| Gram-negative bacteria exhibit stronger resistance to [[Antibiotics]] such as [[Lysozyme]] and [[pennicillin|pennicillin]] G, as well as greater resistance to dyes and detergents. The lipopolysaccharide consists of a core [[polysaccharide|polysaccharide]], Lipid A and O-antigen. This lipolysaccharide layer is important in excluding large hydrophobic susbstances from interacting with the cell. Lipid A attaches to the outer membrane ensuring that the [[lipopolysaccharide|lipopolysaccharide]] remains attached to the cell <ref>Oh S., Antibiotics Attack (http://www.hhmi.org/biointeractive/Antibiotics_Attack/bb_2.html), July 1999, Montgomery Blair</ref>.<br>
| |
| | |
| === References ===
| |
| | |
| <references />
| |
Revision as of 01:31, 15 October 2013