Aquaporin 2: Difference between revisions
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Aquaporin 2 (AQP2) is a water transport [[Protein|protein]] important in regulating water movement in and out of cells. Aquaporin 2 has 6 [[Transmembrane domains|transmembrane domains]]. Loops B and E are important in forming a pore in the middle of the membrane protein through which water can pass. Near the pore on the E loop is a [[Cysteine|cysteine]] residue which when bound by [[Mercury|mercury]] will inhibit the transport of water molecules. | Aquaporin 2 (AQP2) is a water transport [[Protein|protein]] important in regulating water movement in and out of cells. Whilst the [[Kidney|kidney]] removes urine from the blood, Aquaporin 2 is responsible for readsorbing water from the urine. Aquaporin 2 has 6 [[Transmembrane domains|transmembrane domains]]. Loops B and E are important in forming a pore in the middle of the membrane protein through which water can pass. Near the pore on the E loop is a [[Cysteine|cysteine]] residue which when bound by [[Mercury|mercury]] will inhibit the transport of water molecules. | ||
Aquaporin 2 is specifically found in the [[Apical membrane|apical membrane]] of the [[Collecting tube|collecting tube]] of the [[Kidney|kidney]]. When [[Vasopressin|vasopressin]] is released, aquaporin 2 is inserted into the membrane to allow the reabsorption of water into the body. | Aquaporin 2 is specifically found in the [[Apical membrane|apical membrane]] of the [[Collecting tube|collecting tube]] of the [[Kidney|kidney]]. When [[Vasopressin|vasopressin]] is released, aquaporin 2 is inserted into the membrane to allow the reabsorption of water into the body. | ||
Revision as of 15:05, 14 November 2011
Aquaporin 2 (AQP2) is a water transport protein important in regulating water movement in and out of cells. Whilst the kidney removes urine from the blood, Aquaporin 2 is responsible for readsorbing water from the urine. Aquaporin 2 has 6 transmembrane domains. Loops B and E are important in forming a pore in the middle of the membrane protein through which water can pass. Near the pore on the E loop is a cysteine residue which when bound by mercury will inhibit the transport of water molecules.
Aquaporin 2 is specifically found in the apical membrane of the collecting tube of the kidney. When vasopressin is released, aquaporin 2 is inserted into the membrane to allow the reabsorption of water into the body.