Transmembrane domains

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Transmembrane domains are stretches of residues of integral membrane proteins that span across the membrane bilayer. They are key in a wide range of integral membrane proteins including receptors for Growth factors and Hormones, channel proteins and two-way membrane transporters. Most transmembrane domains span the membrane 1-17 times, the most common being 1, 4 or 7 (G-protein linked receptor for example)[1].

References

  1. http://www.els.net/WileyCDA/ElsArticle/refId-a0005051.html
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