Asparagine: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
Nnjm2 (talk | contribs)
No edit summary
130024257 (talk | contribs)
No edit summary
Line 14: Line 14:


<br>  
<br>  
[[Image:Asparagine.png]]


=== References  ===
=== References  ===


<references /><br>
Berg, J. M., Tymoczko, J. L., &amp; Stryer, L. (2002). Biochemistry (5th ed.). New York: W.H. Freeman.<br>

Revision as of 14:44, 29 November 2013

Asparagine is a non-essential amino acid. Its abbreviations are Asn or N, and its codons are AAU or AAC.

It provides an important site for asparagine-linked glycosylation (N-glycosylation) within peptides [1].


Synthesis

                          (transaminase)                                (asparagine synthase)

Oxaloacetate                   ⇒                        Aspartate                  ⇒                     Asparagine

                 glutamate   →  alpha-ketoglutarate               glutamine  →     glutamate

                                                                                     ATP   →  AMP + PPi


References

Berg, J. M., Tymoczko, J. L., & Stryer, L. (2002). Biochemistry (5th ed.). New York: W.H. Freeman.

  1. Kenneth W. Joy, Robert J. Ireland and Peter J. Lea, 'Asparagine Synthesis in Pea Leaves, and the Occurrence of an Asparagine Synthetase Inhibitor' Plant Physiology (1983) 73:165-168