Asparagine

From The School of Biomedical Sciences Wiki
Jump to: navigation, search

Asparagine is a non-essential amino acid. Its abbreviations are Asn or N, and its codons are AAU or AAC.

It provides an important site for asparagine-linked glycosylation (N-glycosylation) within peptides [1][2].


Synthesis

                          (transaminase)                                (asparagine synthase)

Oxaloacetate                   ⇒                        Aspartate                  ⇒                     Asparagine

                 glutamate   →  alpha-ketoglutarate               glutamine  →     glutamate

                                                                                     ATP   →  AMP + PPi


Asparagine.png

References

  1. Kenneth W. Joy, Robert J. Ireland and Peter J. Lea, 'Asparagine Synthesis in Pea Leaves, and the Occurrence of an Asparagine Synthetase Inhibitor' Plant Physiology (1983) 73:165-168
  2. Berg, J. M., Tymoczko, J. L., & Stryer, L. (2002). Biochemistry (5th ed.). New York: W.H. Freeman.

Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox