DNA topoisimerase: Difference between revisions
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[[DNA|DNA]] topoisomerase plays an impotant role in breaking the [[Phosphodiester_bond|phosphodiester bond]] by binding covalently onto the DNA backbone [[Phosphate|phosphate]]. It acst as a [[reversible nuclease|reversible nuclease]]. This whole process is a reversible one, whereby before the [[Proteins|protein]] leaves, the phosophodiester bonds are re-made. There are two types of DNA topoisomerase, [[DNA topoisomerase I|topoisomerase I]] and [[DNA topoisomerase II|topoismerase II]]<ref>Alberts, BA, 2008. Molecular Biology of The Cell. 5th ed. New York: Garland Science.</ref>.<br> | |||
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Revision as of 07:01, 12 October 2014
DNA topoisomerase plays an impotant role in breaking the phosphodiester bond by binding covalently onto the DNA backbone phosphate. It acst as a reversible nuclease. This whole process is a reversible one, whereby before the protein leaves, the phosophodiester bonds are re-made. There are two types of DNA topoisomerase, topoisomerase I and topoismerase II[1].
Reference:
- ↑ Alberts, BA, 2008. Molecular Biology of The Cell. 5th ed. New York: Garland Science.