SSRI: Difference between revisions
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Some examples of SSRIs include [[Fluoxetine|fluoxetine]], [[Paroxetine|paroxetine]] and [[Sertraline|sertraline]] <ref name="[1]">Rang, H.P., Dale, M.M., Ritter, J.M., Flower, R.J. and Henderson, G., 2011. Rang and Dale's Pharmacology 7th ed. London:Elsevier Inc.</ref>. | Some examples of SSRIs include [[Fluoxetine|fluoxetine]], [[Paroxetine|paroxetine]] and [[Sertraline|sertraline]] <ref name="[1]">Rang, H.P., Dale, M.M., Ritter, J.M., Flower, R.J. and Henderson, G., 2011. Rang and Dale's Pharmacology 7th ed. London:Elsevier Inc.</ref>. | ||
=== References === | === References === | ||
<references /> | <references /> | ||
Revision as of 05:58, 19 October 2015
SSRI is an acronym for Selective Serotonin Reuptake Inhibitor. SSRIs are antidepressants [1] that work by inhibiting serotonin (a.k.a. 5-hydroxytryptamine or 5-HT) re-uptake. Unlike tricyclic antidepressants (TCAs) and serotonin/norepinephrine reuptake inhibitors (SNRIs), SSRIs have greater selectivity for the serotonin transporter than to norepinephrine transporter (Whalen, Finkel & Panavelil, 2015, p. 136)[2]. Therefore, SSRIs are more specific, inhibiting only serotonin reuptake (Whalen, Finkel & Panavelil, 2015, p. 136)[2]. This in turn will increase the serotonin level across the synaptic cleft.
Some examples of SSRIs include fluoxetine, paroxetine and sertraline [1].