Adrenegic receptor: Difference between revisions

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Adrenergic receptors respond to [[Adrenaline|adrenaline]] and [[Noradrenaline|noradrenaline]] and can be found in a variety of different tissues.  
Adrenergic receptors respond to [[Adrenaline|adrenaline]] and [[Noradrenaline|noradrenaline]] and can be found in a variety of different tissues.


Adrenergic receptors can be sub divided into two major classes: α and β.  
Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.


Adrenergic receptors can be further subdived into α1 , α2, β1 and β2.  
For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.
 
For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.
 
α-Adrenoreceptors are subdivided into two subgroups, α<sub>1</sub> and α<sub>2</sub> receptors.
 
β-Adrenoreceptors are subdivided into two subgroups, β<sub>1</sub> and β<sub>2</sub> receptors.


Adrenergic receptors are [[G-protein Coupled Receptor|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>  
Adrenergic receptors are [[G-protein Coupled Receptor|G-protein coupled receptors]]. <ref>Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.</ref>  


=== References ===
=== References ===


<references />
<references />

Revision as of 03:44, 21 October 2015

Adrenergic receptors respond to adrenaline and noradrenaline and can be found in a variety of different tissues.

Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.

For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.

For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.

α-Adrenoreceptors are subdivided into two subgroups, α1 and α2 receptors.

β-Adrenoreceptors are subdivided into two subgroups, β1 and β2 receptors.

Adrenergic receptors are G-protein coupled receptors. [1]

References

  1. Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.