Adrenegic receptor

From The School of Biomedical Sciences Wiki
Jump to: navigation, search

Adrenergic receptors respond to adrenaline and noradrenaline and can be found in a variety of different tissues.

Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.

For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.[1]

For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.[1]

α-Adrenoreceptors are subdivided into two subgroups, α1 and α2 receptors.

β-Adrenoreceptors are subdivided into two subgroups, β1 and β2 receptors.

Effects mediated by adrenoreceptor (when activation):

Adrenergic receptors are G-protein coupled receptors. [2]

References

  1. 1.0 1.1 Whalen, K., Finkel, R. and Panavelil, T. (2015). Lippincott's Illustrated Reviews. Philadelphia, Pa.: Wolters Kluwer.
  2. Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox